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Ollie Campbell

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April 27, 2026

GLP-1 Medications Are Changing the Game. Here's What That Means for Your Training.

There's a conversation happening in gyms across the country that most coaches aren't having openly. Clients are losing weight faster than before. Their appetite is suppressed. Their energy patterns are different. And quietly, a growing number of them are on GLP-1 medications like Ozempic, Wegovy, or Mounjaro.

We're having that conversation at P6. Openly. Because pretending it isn't happening helps nobody.

The Problem Nobody's Talking About

GLP-1 medications work. For many people, they're a genuine medical breakthrough for managing weight, blood sugar, and metabolic health. We're not here to debate that.

But here's what the prescription doesn't tell you: weight loss without structured strength training doesn't just burn fat. It burns muscle too.

Research consistently shows that when people lose weight rapidly, whether through medication, aggressive calorie restriction, or both, a significant portion of that weight loss comes from lean muscle mass. Some studies suggest it can account for 25 to 40 percent of total weight lost when resistance training isn't part of the picture.

That's a serious problem. Not just for how you look, but for how you age, how your metabolism functions, and how well your body holds up over the next decade and beyond.

Losing muscle while on a GLP-1 medication means:

Your metabolic rate drops, making long-term weight maintenance harder.

Your strength and functional capacity decline.

Your bone density takes a hit.

The risk of what researchers call "sarcopenic obesity" increases, where body fat creeps back but muscle doesn't.

The medication handles the appetite. Nobody's handling the muscle.

What the Research Is Starting to Show

The fitness industry is paying attention. The National Academy of Sports Medicine's 2026 survey of over 600 fitness professionals identified GLP-1 medications as the single most disruptive force reshaping how coaches work with clients right now.

The conversation is shifting from "how do we help clients lose weight" to "how do we help clients preserve what matters while they do."

That means the role of a good coach, in 2026, is no longer primarily about burning calories. It's about building and protecting muscle, educating on protein, and programming for long-term metabolic health.

This isn't a small shift. It's a fundamental change in what effective fitness coaching looks like.

Why Strength Training Is Non-Negotiable If You're on a GLP-1

Your body needs a reason to hold onto muscle. That reason is resistance training. Without it, the body has no signal to preserve lean tissue during a calorie deficit. Think of it like calluses on your hands, there's a reason why a chippy's hands are the way they are, there's a stress, so the body responds! The medication suppresses your hunger, but it doesn't send any signal to your muscles to stick around.

Here's what the evidence supports for anyone using a GLP-1 medication:

Train at least three times per week with resistance. This doesn't have to be complicated. Compound movements, progressively loaded, done consistently, give the body the stimulus it needs to retain muscle while in a deficit.

Prioritise protein intake. Most people on GLP-1s are eating significantly less. The risk is that they're also eating far less protein. Aim for at least 1.6 to 2.2 grams of protein per kilogram of bodyweight daily. This becomes harder when appetite is suppressed, which makes intentional food choices more important, not less.

Track strength, not just scale weight. The scale going down is not the only metric that matters. If your strength numbers are dropping significantly alongside your weight, you're losing muscle. That needs to be addressed.

Don't avoid the weights because you're tired. GLP-1 side effects, particularly in the early stages, can include fatigue and nausea. The temptation is to skip resistance training when you're not feeling great. Working with a coach to adjust intensity while maintaining frequency is the right answer here, not stopping altogether.

What P6 Is Doing Differently

Priority 6 was the first gym in Oxfordshire to openly acknowledge and support GLP-1 users. Not because it's a marketing angle. Because it's the right thing to do for the people walking through our doors.

We've built our coaching around the Six Pillars: Mindset, Movement, Strength, Nourishment, Recovery, and Connection. Every one of those pillars matters for someone navigating weight loss with medication support.

If you're on a GLP-1 and you're not strength training, you're leaving the most important part of the equation undone. You're managing your weight but not building the body that sustains your health long term.

We work with people in exactly this position. We help them:

  • Build a strength training programme suited to where they are right now, not where they were two years ago.
  • Understand protein targets and how to hit them when appetite is suppressed.
  • Monitor progress in ways that actually reflect health, not just the number on a scale.
  • Stay consistent through the side-effect phase and build habits that outlast the medication.

GLP-1 medications can be a powerful tool. But a tool is only useful when it's part of a broader plan.

The medication handles appetite. Strength training handles muscle. Nutrition handles the quality of what you're putting in. Recovery handles how well your body adapts to all of it.

None of those things work in isolation.

That's exactly why a coaching-led environment exists.

If you're on a GLP-1, already thinking about starting one, or working with someone who is, come and have a conversation with us. No judgement. No agenda. Just an honest discussion about what your training should look like to support where you're going.

That conversation is free.

Book a No Sweat Intro at https://www.priority6.co.uk/contact-priority-6-in-abingdon-uk.

Priority Six | Abingdon's longest-standing CrossFit gym | Strength, Performance, Longevity, Transformation www.priority6.co.uk | @priority6 | ollie@priority6.co.uk

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